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Cleveland Clinic and Siemens Healthineers have signed a new 10-year deal to upgrade imaging, cardiology and radiation oncology care across the health system. The agreement builds on a partnership that dates back more than 35 years and includes the supply of equipment like magnetic resonance imaging (MRI), computed tomography (CT) and X-ray systems. Officials said the collaboration aims to make the patient experience more personal while giving clinical staff new tools and training.

Cleveland Clinic, a nonprofit academic medical center based in Cleveland, operates hospitals and outpatient locations across Ohio, Florida, Nevada and international sites in London, Canada and Abu Dhabi. Siemens Healthineers, a global medical technology company, has worked with the health system for more than 35 years, producing over 100 research projects and 70 peer-reviewed publications, according to the companies.

Under the terms of the deal, Siemens Healthineers will supply Cleveland Clinic with imaging and treatment equipment. This includes systems for radiation oncology and interventional radiology, which uses imaging to guide minimally invasive procedures. The company will also add staff to its on-site team, which already includes more than 30 employees. Some of the new hires will help Cleveland Clinic build a theranostics cancer-treatment program, an emerging approach that pairs targeted imaging with therapy to personalize cancer care.

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Cleveland Clinic will also become a training site for Siemens Healthineers’ MRI technologists, offering hands-on clinical education, protocol training and radiation-safety instruction. The deal supports plans to expand how doctors use CT scans in cardiology, radiation therapy and image-guided procedures. The companies said the partnership could also lead to new research, training programs and software that automates parts of the imaging process, along with plans for biomedical engineering training programs in the Cleveland area.

“Through our longstanding relationship with Cleveland Clinic, we have achieved important advances in the diagnosis and treatment of serious disease resulting from more than 100 research projects and 70 peer-reviewed publications,” John Kowal, president and head of the Americas at Siemens Healthineers, said in the news release. “We look forward to many more years of innovation and continued positive impact on patient care.”

The deal is expected to bring economic benefits to the region, including new jobs and investment in Cleveland Clinic’s main campus, along with continued growth of the Cleveland Innovation District, a life sciences and technology hub the health system anchors with IBM and other partners. Cleveland Clinic’s move into theranostics comes as more health systems adopt the same approach to treat cancer.

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Market analysis from DataM Intelligence shows the global theranostics market was worth $2.69 billion in 2025 and is projected to reach $7.56 billion by 2033, representing a compound annual growth rate of 15.4%. That figure reflects how fast the market is expected to expand each year, on average, through 2033.

For patients handling complex care pathways, the integration of theranostics into standard workflows offers a practical shift from generalized treatment to highly targeted interventions. This approach relies on identifying specific biological markers within a patient’s tumor to determine the most effective radioactive agent, ensuring that therapy is not only more precise but also better tailored to the individual’s specific disease profile. By centralizing these capabilities within a major academic health system, the region aims to reduce the variability often found in specialized oncology care, potentially shortening the time between diagnosis and a tailored treatment plan.

“This strategic alliance with Siemens Healthineers will help us bring more consistent, connected and advanced imaging and treatment services to our patients,” Peter Liu, M.D., chair of enterprise imaging at Cleveland Clinic, said in the release. “By aligning technology, service and clinical support more closely across our global health system, we can improve access, increase efficiency and create a better experience for patients. This collaboration builds on a strong foundation and positions us to continue innovating for the benefit of our patients and communities.”